giriinthejungle

There are good answers about differentiation from stem cells, process governed by the evolutionary determined genetic information stored within the cell itself. This genetic information was/is influenced by environment but that influence tends to be slow and subtle.

I have another answer to contribute. Metastatic cancer cells. These are cells which detach from primary tumors in any part of the body, then have to break into the lymph or blood and then they in a sense "decide" where they want to settle. We now know they'll have preferences: some cancers will metastase to liver, some to lung, some to brain; but before they do so, these cells will literally circle around the body, searching for a "perfect spot". Once they find it, they settle, often entirely changing their O.G. tumorous behaviour in the process which in return makes them super unpredictable and hard to kill. And all it takes is one wandering cell.

I missed this in the news, then saw link refers to Kronen Zeitung report which is not a great newspaper to cite so thought for sure it cannot be entirely true? But it is! And here another link from Die Presse (google translate works fine here) which tells us it was not a jerk dad who brought his kid to drill holes but an idiot mom.

I think it's Lay it on me by Vance Joy. It has a part about him being sad, then there is love, and then an instrumental chorus to which I dance to (given a chance). I guess I find it pretty uplifting.

This is beautifully said. There had been moments in my life when I'd be so very happy that I would indeed close my eyes, take a deep breath and appreciate the moment. When there is nothing to bug you in the back of your mind to ruin the setting, such moments are beautiful and I agree, could be described as pure joy.

Also, metals can easily accommodate varying number of electrons in the electron shells of their atoms and still be stable. That makes them very good to quickly store and release electrons which means they can help say transfer molecules around (iron for transport of gasses), scavenge free radicals (e.g. manganese) etc.

This is excellent!

It can really depend where you live so I think the first advise is to take it easy on yourself.

• It is ok to combine ways of transports, say cycle to the first train/bus then load the bike on it/park at the station
• Start with a sturdier bike, the one which is bigger and more visible in traffic and gives you a better sense of control.
• don't expect cars to respect you because you cycle or to know what to do around you. Bad drivers are everywhere. Don't try to prove points. Safety is more important than ego.
• get yourself a good, large backpack. This will be your new back seat
• Take taxi/uber when needed. I once arrived to a friend's wedding held out of town in a taxi and literally everybody I knew there looked at me as I was either a fool or a millioner. The bill was like 35$. Way cheaper than owning a car.

Lastly, enjoy how good you will feel. Climate protection and all that is great but your body will love you for it and you will feel it. Good luck

Trees! Those big, old giants which make you feel like they are indeed harboring some ancient wisdom, being there, in the same spot years before you, barely brushed by the passing of time. And then if they are evergreen not even season affects them - they just keep on existing, all tall and gracious. How awesome is that.

Not to mention academic/research text where authors are actually forced to pay to publish, only to have the articles end up behind a pay wall of given journal. If the authors want their papers freely available, they have to pay extra fees to the journal (we are talking thousands of dollars scale). Not a cent goes back to the authors or even research funding bodies. Long live Libgen!

Make trains cheaper goddammit

Do you use diluted or out-of-the-bottle vinegar and does the fruit taste weird afterwards? I need to temporarily become a bit of germophobe and this sounds like a good way to take care of fresh produce.

It doesn't refer to the interaction of liver with stones. The bile acids are produced in liver then transported to the gallbladder, where they are stored and released into the intestine when needed. The whole role of gallbladder is to accept and release the bile salts, the "stuff that liver makes". But then sometimes gallbladder makes stones and it has to be removed because of it.