• Io Sapsai 🌱@lemm.ee
      link
      fedilink
      arrow-up
      38
      arrow-down
      1
      ·
      3 months ago

      Eh one every now and then is fine, I take it for motion sickness when going on long car rides. Half a pill is enough. Then again, taking enough to get nightshade-like poisoning is really not recommended.

      • candyman337@sh.itjust.works
        link
        fedilink
        arrow-up
        32
        ·
        3 months ago

        Long term use has now been linked to neurological issues, it crosses the blood brain barrier. However, yes occasional use is relatively safe. But it is not recommended as a daily antihistamine at all these days.

        • Io Sapsai 🌱@lemm.ee
          link
          fedilink
          arrow-up
          4
          ·
          3 months ago

          Oh yes, I’m completely aware. I’m a pharmacist with allergies. I always try to talk my patients out of first-gen antihistamines. Bilastine is my go to these days for myself. Zyrtec and generics as OTCs.

      • swab148@lemm.ee
        link
        fedilink
        arrow-up
        4
        ·
        3 months ago

        Can you expand on that? I take melatonin every day, have I been poisoning myself?

        • Kraven_the_Hunter@lemmy.dbzer0.com
          link
          fedilink
          arrow-up
          11
          arrow-down
          3
          ·
          3 months ago

          It’s more of a placebo than an actual sleep aid. It’s not harmful though. If you want to take it, don’t worry. If you think it helps, then in some small way it does.

            • JoeBigelow@lemmy.ca
              link
              fedilink
              arrow-up
              2
              arrow-down
              4
              ·
              3 months ago

              But if you NEED to fall asleep in the next hour 25-50mg of diphenhydramine, 1-2 normal Benadryl or Advil/Tylenol/Motrin PM(with they’re active ingredients) does a pretty reliable job if you let it. You have to get in bed and give it a shot at working but I find little failure with it. You will however be somewhat groggy in the morning, drink water.

        • dmMeYourNudes@lemmynsfw.com
          link
          fedilink
          arrow-up
          4
          ·
          3 months ago

          It’s most useful to take 2-3 hours before bed to reset your circadian rhythm. Essentially it mimics the melatonin you make at sun down to prepare your body for sleep. You only need 1-2 mg to do this.

          • JoeBigelow@lemmy.ca
            link
            fedilink
            arrow-up
            3
            ·
            3 months ago

            I even think 1 mg is too much. It’s active in microgram doses. Also read the Wikipedia page, it’s poorly regulated and pills can contain upwards of 4x what they say.

        • meowMix2525@lemm.ee
          link
          fedilink
          arrow-up
          2
          ·
          3 months ago

          I’ve heard of people developing a dependence on it when taking it regularly. Especially kids.

          I use it a couple times a year for the occasional restless night and it seems to work for me.

          It’s not inherently harmful afaik but it could disrupt your sleep if for any reason you have to stop taking it.