Another of my posts from Reddit in recent weeks:

Does anyone else experience an increase in DOMS (delayed-onset muscle soreness) after starting zepbound? I have ramped up the intensity of my workouts lately, and it seems like muscle soreness has gotten much worse.

I’m thinking I should dial it back a bit, because it is also stimulating quite a bit of appetite. Not really what I want when I’m trying to cut calories and weight. 🤔

Addendum: The consensus was that a lot of people experienced more difficulty completing endurance workouts, but not specifically weight training (which is where DOMS usually comes from).